Upstream Process Development Science Manager

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Upstream Process Development Science Manager Apply
locations
Nottingham
time type
Full time
posted on
Posted Yesterday
job requisition id
R31624
We are looking for an Upstream Process Development Science Manager to join us at our site in Nottingham.We are looking for an Upstream Process Development Science Manager to join the Technical Support Group at Albumedix, now part of Sartorius. In this role, you will be responsible for leading a small close-knit team in upstream processing activities to produce recombinant protein products in small and pilot scale fermentation.The overall team in the Technical Support Group consists of 15 professionals, and we are looking forward to shaping the future with you. The site is expanding so it’s a great time to join the team to further your career.This position is available full-time. It is an onsite role in central Nottingham and the site is easy to get to, being a short walk from the trains station and tram stop.Grow with us –
Your Responsibilities
You will be responsible for management of the upstream process development team, training and mentoring staff in the group and when required in the wider organisationYou will also implement individual development plans, goal setting and performance review for the teamYou will spend most of your time in the research laboratory to provide technical support for biopharmaceutical manufacturing of recombinant human albumin products, expert analysis of upstream process steps (shake -flask, seeds, main fermenter, cell separation) as well as new product developmentYou will lead upstream activities, perform troubleshooting, and process optimization using scale down fermentation studies, with subsequent implementation at production scale.You will implement process improvements with respect to yield, efficiency and/or robustnessIdentifying process optimisation activities, including Design of Experiments (DoE), performing scale down studies, and management of their implementation at large scaleCarrying out fermentation experiments using different scale benchtop bioreactors (2L) and pilot bioreactors (20-200L), this includes SIP, CIP, media preparation, seeding, inoculation, fermentation monitoring, microbial, chemical analysis and harvestingReview of batch process data and contribute to continued process verificationSupport technology transfer projects for cGMP manufacturing to other sitesInvestigation and recommending of new technologies to use in upstream processesIn addition, you will provide fermentation support to cGMP cell bank testing, as well as generating albumin-based products for enhanced service projects and for application areasYou will prepare, test and release laboratory growth media, preparing reagents and buffers as necessary as well as interpret results, prepare data summaries and reports and recommend future actionsWhat will convince us PhD degree in Fermentation, Biotechnology, Microbiology, Biosciences, Life Sciences or related discipline with at least 5 years of relevant fermentation industry experience or MSc degree with at least 10 years relevant fermentation industry experienceExperience leading or supervising a small team would be essentialExperience in microbial fermentation, preferably yeast fermentation would be essentialExperience in aerobic fermentation would be desirableGood understanding of fermentation, growth rates, process optimization, developing and scaling processesWell-developed independent research skills, including statistical analysis, data analysis and Design of Experiments (DoE) for process optimisation using relevant softwareHands on experience with Sartorius fermenters such as Biostat B – DCU and D- DCU would be desirableThe ability to convey information clearly and effectively both in speaking and writing, to articulate goals and facilitate open discussions The ability to inspire, motivate and lead the team by exampleFoster a collaborative environment and encourage positive relationshipsThe ability to adapt to new situations and being open to change and manage transitions smoothlyIn order to commence working with us, the successful candidate will have the right to work in the UK.What we offer As a growing global life science company, stock listed on the German DAX and TecDAX, Sartorius offers a wide range of benefits: Personal and Professional Development: mentoring, leadership programs, LinkedIn Learning, internal seminar offeringsWelcoming Culture: Mutual
support, team-spirit
and international collaboration; communities on numerous topics such as coaching, agile working and
businesswomen network Health & Well-Being: Wide section of health and well-being support such as healthcare plans and health assessment services Intelligent working environment: Working in smart buildings with the latest technology and equipment (please check if applicable for position)AlbumedixBenefitsAttractive Working Conditions:35 hours working week25 days annual leave, plus public holidaysFree parking on site, easily accessible from the city centre and transport hubsSocial Committee – With both free and subsidised social eventsPrivate HealthcarePension SchemeFree onsite fitness classesGroup Life AssuranceGroup Income ProtectionFree annual flu vaccinationsEmployee Assistance Programme for colleagues and their familiesOne day per year given to be a ‘Helping Heart’ within your local communityAbout Sartorius Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.Join our global team and become part of the solution. We are looking forward to receiving your application.
www.sartorius.com/careers
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